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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12efae32e8c5c26abf1f0535c7c68c44c2f92c77a950f1363b832e406cace3af' 
  AND token = 'bs8WMlX95M67w12IBZ8H+oQzDYoIS5WEfVwvamL+iqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}