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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0516d20f89426ab21ed585a941262d6abb095e97889453066aeaf5f85c28f3a4' 
  AND token = 'tVDUFkJ7/e9IiEXVlk8aDZkN5A8mp4oFIT+4hpEWXQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}