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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8e98f93f36d86c2686002a86e8d3aa19040b1d4e2fbb6f730ea20bd73fd669' 
  AND token = '78G0+omgVBanf7vvqHIC1TA+NVaaUk6h0KY6SI6J0QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}