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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4918e3ca311de0df066b35b43f4b8eef1c8102a58909e6ec35e07d298704846f' 
  AND token = 'OMkW0dGfpc2EOM6NDhLL2vR27WpM7wp4R23pyRiMGDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}