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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c9a36088b87804c0ec9ce1eeb97d2954e2498e182351cd9faca0601172caa3' 
  AND token = 'djFL25w1+zGkDTGNGuRwDtJ/ShJH6RCRtlSdIcKncHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}