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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422c0756ebffa81a3eb5a3c4d200d4b9a04b0729b70a5bc0f6e78e07b9291f73' 
  AND token = 'ntpC8TXs6WFG3FHyuPsmbXJmyPkNam3vwGg8/9TmFlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}