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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '763a2261d4aa9917b89817b426d1c8adf34851c3e831d9d5887d040207a8c822' 
  AND token = 'Z1+L8I6Rvzh5TMyyZq9WRN4haj3oK7nR2SkTyp/5ryQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}