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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8244dd4b53bb8705917024da36c326ed7bd69d4ce0e16b73ed489dfc417c72' 
  AND token = 'X0+j/qhfY7efNigZEnIlsqylXgxZe2DIpLRwQB7Nc90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}