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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66d12b23e81e3936db1c2e9b656c605a6659100dc6d995752095113fa5ba0b1' 
  AND token = 'v8C9XG0Byv5zasjlW/Qf3wR5ZMk/aQt+CINXxKtXzmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}