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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d24e4cf0a21251722998551c8f271981ef49ea3a9e2aaf6b459b78544b98b1e' 
  AND token = 'QlA3RmUS+T3sbkrTHKS2LsCl5SVIoj9xILCqfXJi5/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}