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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb1a934dd4f0cc97b67d14009fbe499ebbb8225fdaf9f46b4b90e09941f635a' 
  AND token = 'VCYxJubVJ0uoOcfjvsEOPq0vEmU79aZhXuozomIsYdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}