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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e74289df94470bdb298c9aa8953af25bf28643a4a4c9592a5fdf77163788797' 
  AND token = 'SmG1mNlV/RiWKgWWqS9WlXhsWiuncc2uObIbDU6thZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}