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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9e8142ecbb21f269afd3368bc5b5a115e420d2aedaab1145805663d4f44259' 
  AND token = 'HtZd4F9jusiRioG9UwepWSj6TDZYm//BOy49CU/i9Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}