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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69cd3d301f6e5bdc09555e8c29ed3470fc180b44a10eedc1a570439763a7a0ac' 
  AND token = 'hTNIfhR6BQvbxmjHM/qYyN5q2ZwkDBmC5NoFYPp6Oqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}