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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a36ede0c70720a800238645333d5cad49a5d8a4c776cf3d10ed45ae06e37f017' 
  AND token = 'HtqF1vhvyl0XFUEH4rTMkeeNfijFgK2mBL6PUnmjRxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}