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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8f22658f00010c134e256b7e80f23f7cdcffc32bf871e9b13ea7c6c9213c04' 
  AND token = 'heUggxJcOz6B6V2Ps7GQOYMwx/gaLGDCfCxNgFD2I3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}