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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cf5c3f23dee114ef103aa689024183c64fae86b1393c56538fc98158bda290' 
  AND token = '+75f5kG5NPpgh+IvYTHxyvSM74kjqqMKo4U1/AidyX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}