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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51324f8b48f93438543b9d916689e3ca51198af3b21bd97028dbc05ee3079e10' 
  AND token = '3jwUtIIIb+AJ99kQCqsqPo6KeTiO3Vrq6W/RAQjq0UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}