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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7380e2a7ff7f7f7e7fa63150f6be31cb2c78e13d6d853a6bceaa2c6f4e57c487' 
  AND token = 'gRMT1MFzmlKuFeQYJAIAIAhN6A+JCF4Sz4B+GsgGRdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}