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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b11453c50d81c6624eb4a2b61a304b66e5661d671941d5c0a81a65533c4a71' 
  AND token = '6f0Jrf6pYYbAaXqmEDfc0EbnoCgqycIR5wGBj4ja9M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}