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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57922e877b3a7ab213dadba45f73100cc05825296a3c205e022605538c704aea' 
  AND token = 'XAJUNqS5u7EziFL+dqD8YK0uD8wo5XTnCJk65/Sez/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}