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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8ccb28132297aeca7235cc8e20123b9e72dc04766fde189cbebc34cf15a7cf' 
  AND token = 'De/RuP6putS6Gz0JLf3vAm2r4WavewIfEmbNEogy8/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}