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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3699328ef7a50f7d2a3f3251a5dc01985f713ee7f8fa2329b7225f66827411' 
  AND token = 'fIK017ePUxmZbF1dGofRJG2lAUmxFr2SN5h+lcTCjto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}