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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4718645d9d5d5987bf07c9eff376960bf5d158f41cd8b51902dfde6b221b96e8' 
  AND token = 'n8zYf7wpF1sd+egz+ielEH6BuucM7xmZsgxxUqNZc9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}