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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2528fe344ce309e2fa6e91f7a8cf3cfc017ad47484e9cce5d281f9816058c78' 
  AND token = 'q9oI33kM/y64RhKE8/Rnv0rsUzsXstpeSzEQ4Kg8mIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}