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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d2b813615b25cc8a061c3f7c088851b09c8b916c1b59aad856a919c5e4f40d' 
  AND token = 'upBcekobntJ4HUGjGS1V2b2NPTmkt4TOfyRPRAJ//6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}