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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857b4f42f8e64d63acc9da994b19e5bb3989f32d1e59a7a2e3b4e9c07f13f0e5' 
  AND token = 'tMPhRvl/Yq980leHlf4jdU/kIccZUIk0p6ir5u4EVTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}