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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb490153509276dd331923d524201c489b4e7b7b53a0310006db8f12c160a9f5' 
  AND token = '4ae1TEKTwhbBynKKyRrDmcolyFOC1lfdtflZRVW63zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}