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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0242f3da7d54a1d960cbb1cd35718fbf99de3a59a890a22cb3201f6fc306da64' 
  AND token = '1kIrJBCyodik+wMSy4+VLweKMkLPH9ycsnwcHWrSN5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}