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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6f66ea9ba196771adcc387c6eedfdb6c53b94ed6840151f4dadb0fba12b755' 
  AND token = 'nmhMIen1rae+WgQz3NX587Fkt+SMrJGdENVmz/XsbrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}