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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45594af73b32d7cd7bfd87b9d6789e99ef26753a2de77d8304c261c30dadff04' 
  AND token = '8P6PPEQO3W9yg6+dpsiy+wQ+xSdM6UkYyAbDONJefn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}