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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c173b8de0bc283932b658e8b49c3227a559aba1087bd7548db25e5b5addc96d' 
  AND token = 's6ii6N7StpgQ6j91p/Y/Nzk+u1BCjnk/ZqYWq8ydSsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}