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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c95a17c4f7aa0f95fdf253e3d30c3b7cb6314b67a03aa2d041be51c9429d27b' 
  AND token = 'a+3qJg6mtgO3osmq/gDSERWyhdBKlcI6qDGrs/9nplw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}