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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a4f5e378ffcc8016fed4a75189a2533f8e8343e991afbd05e0106a7d3913df' 
  AND token = 'xeWI+U3nndLrpyC6TF1atg5ODMVBXW4muqfUIQrzoAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}