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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a8ed2864d923ccbd505e590255b61810c93b6dc34d9b50d4493acaaa0606f8' 
  AND token = 'MeKwpuF/iAlXyRPMBMRrGA3C0G7w4UraMQf9N0AmxIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}