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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86af4298cdaf159d94492f51a043f595822c15d63733d64946a4a92bd2bdcc2b' 
  AND token = '1oZtV3Au5rg49TO+67Zoqt9M1aP2o5RlTpSoTquHuMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}