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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e875164f0ec4fe04dac321a94ccece83b9ab70a7a3f775e694023f8d39111fd2' 
  AND token = 'Ux6Wrf3ECWgPOEbudRXfV3291sqLVzOFbphJ6uIWJAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}