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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f141fbaf4214195c96a71b807302f7a40fcf1c81aa4ceff8e41bb1f3356f2bb' 
  AND token = '+Z89wuZGsboKb1caPz8kED4Ktu2dHUAL7zz+HXzwHLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}