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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed28986dc17023d5b63b79320e00f7232649ac41adb2481f39e78a04352aaf1a' 
  AND token = '4O/aoEs6jojrSWTHukhmGh3qUr2TB5hdLfaRHKtIBJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}