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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd1c005295fb931ed23a18c49f8a1e5b6d6c06a4281f72f88f42d66a23c741bc' 
  AND token = 'JKg9uKVcb7Ex2d080q2WNhB+8eUgPpyugXdU42wPjhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}