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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e20b66500e8fe3d4090fa3661e8effdd09c08386a1e090d6b2e5675a0b49f4ed' 
  AND token = 'DcNtBFDTZ8v4awe0haadwiPVg7E3IHR3rs/0AxPORaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}