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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e260b47bfb21122bf4f820b201b5111d5db26b250318bc094499385f9b80e6' 
  AND token = 'HO2q/AuLgd38juJX5DuBCfSyhNEQYoRj8m/9zjwFisg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}