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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ece6b8f8bc37dbd08fa933a3693e73e4a3aab83356b1ea7878bd32462ff929' 
  AND token = 'ZSXXOczhjWXc+5X31P2or/bIGcbgmZjAD0aUVxbr0DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}