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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2dd38456a503d4a63afa71d47ce4b5387872ee5ea920452f16477769e4a7615' 
  AND token = 'ugTzhJNO021RBU9MEGnYcaEbRPPS6OAdeTPEMRlZl9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}