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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1594d758a7f87b430b73f7e37fd787eefcb09228ea587f6bc5359c79246ffb3' 
  AND token = 'xT0QD/YCoyOBYngh0hj7lEdrsIPYD/zJ0MEeX50UpMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}