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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c61a9b51cb495debfb821bbee6f1fd54df102ec1604ce2b866fab6bf66c1491e' 
  AND token = '+IQIke/+YLLzBzP82WwVqICGEqZq5pRBP9onX9tdUN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}