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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44041b6456f8b702a6ca5958a8dee1ce3ed49c8993b7a4a5b1807f1420da7b8b' 
  AND token = '1D45vbNQYUmp59QMWofZcx6HmuNjkh1ANY46bdg00wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}