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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de64a385f8f0e23e42f776c890ad6db6ecc3a15be392e60acc4e81303df376e6' 
  AND token = 'fJlzH+1hAsBdR7O79nja5c2kq6SNz6f3sJNpq/QkDhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}