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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed06dbcfa15d75630996c2f232149fd6bd3efc63c417db5277585383adccf501' 
  AND token = 'JKMjltx4yKB0Qp3HEQk5WNaoJBCpNo47HqTE2qBbgO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}