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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6072ad82c9c9ba7fb58d7044be6a41e0889a30e658ca5998241f243c8149675d' 
  AND token = 'IcCxa1Utt65ukS3hLCibqNWwWWW5Vg/gsbAmE23QIoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}